Monday, April 3, 2023

Cleaning a cryoprobe

One of the Skaggs NMRs is normally fitted with a 1.7mm cryoprobe. This piece of equipment is essential for our natural products and metabolomics users who have limited amounts of their samples. The capillary sample tubes for the 1.7mm cryoprobe use special shuttles that do not grip the tube. If the probe gets dirty then the tube can fail to enter the top of the probe and instead gets pushed up out of the shuttle. This becomes apparent when the sample fails to produce a lock signal. Repeatedly ejecting and inserting the sample tube can sometimes get the tube to drop into place by luck, but this is not really a viable solution. If the 1.7mm tubes are not entering the probe reliably then the probe needs to be cleaned.