Homodecoupling is a technique for selectively removing coupling in 1D NMR spectra. Often 1D 1H spectra show complex splitting patterns that are difficult to interpret. Selectively eliminating one coupling may allow a multiplet to be interpreted or enable measurement of couplings that could not otherwise be quantified. Recently, we used homodecoupling to assign the stereochemistry of a pair of enantiomers.
