Wednesday, May 6, 2020

Binding: Saturation Transfer Difference

One of the strengths of NMR is the variety of methods that have been developed to understand different aspects of molecular interactions. The previous post discussed the waterLOGSY experiment, which identifies small molecules that bind to larger molecules. The saturation transfer difference experiment is another method that identifies molecules that bind another, but it relies on a different mechanism than the waterLOGSY experiment and so is often useful in different situations.