Monday, May 8, 2017

Variants of the 1D 13C experiment

1D 13C spectra are often used to confirm compound identity. The simplicity of such spectra enable the number and type of carbon atoms present to be quickly evaluated. 2D 1H-13C correlation spectra, while inherently more sensitive and informative, require more work to interpret and may not show signals from all carbon atoms. Consequently, 1D 13C spectra still have a place in compound characterization. To increase the sensitivity and information content of 1D 13C spectra several variants of the original pulse sequence have been developed. Several of these are discussed below.